IVF & Assisted Reproduction

Common Mistakes That Can Reduce the Chances of Pregnancy After IVF

In short: The main mistakes after ICSI are not taking the medication properly, stress, too much activity or too much rest, smoking (even passive), too much caffeine ( more than about 2 cups of…

In short: The main mistakes after ICSI are not taking the medication properly, stress, too much activity or too much rest, smoking (even passive), too much caffeine (more than about 2 cups of coffee a day), intercourse after transfer, too little sleep (under 7 hours), taking medicines without advice, ignoring important symptoms and testing for pregnancy too soon.

IVF is one of the most advanced infertility treatment techniques. However, its success depends not only on the quality of the embryos or the doctor’s skill, but also on daily habits and behaviors that the patient may engage in without realizing their impact.

Here are some of the most prominent mistakes that can weaken the chances of embryo implantation and a continued pregnancy:

  1. Not Adhering to Medications and Hormones

Medications such as progesterone are essential for supporting the uterine lining.

Mistake: Forgetting doses or not adhering to the prescribed schedule.

Impact: Weakened uterine lining preparation, leading to implantation failure.

  1. Psychological Stress and Anxiety

Chronic stress leads to hormonal imbalances, such as cortisol.

Tip: Worry during the waiting period is completely normal; support from your partner, family or a counsellor, and relaxing activities, can make this time easier.

Effect: Research shows that stress and worry do not reduce the chance of the embryo implanting, so you should not blame yourself for feeling anxious — but managing stress helps your wellbeing and helps you cope with treatment.

  1. Excessive Movement or Complete Rest (Both are Wrong)

Mistake: Strenuous physical activity or complete bed rest.

Effect: Strenuous movement may cause uterine contractions, while inactivity may affect blood circulation.

  1. Smoking (even passive smoking)

Mistake: Smoking or exposure to secondhand smoke.

Effect: Reduces blood flow to the uterus and affects embryo quality.

  1. High Caffeine Consumption

Mistake: Having more than 200 mg of caffeine a day (about 2 cups of coffee).

Effect: May reduce the chances of implantation and increase the risk of early miscarriage.

  1. Sexual Intercourse After Embryo Transfer

Mistake: Engaging in sexual intercourse without consulting a doctor.

Effect: May stimulate uterine contractions at a sensitive time.

  1. Unbalanced Diet

Mistake: Excessive consumption of sugars and fast food, and a deficiency in protein and vitamins.

Effect: Poor quality of the uterine lining and hormonal balance.

Best: A diet rich in protein, iron, and omega-3 fatty acids.

  1. Lack of sleep

Mistake: Sleeping less than 7 hours a day.

Effect: Hormonal imbalance that can affect pregnancy implantation.

  1. Using medications without consultation

Mistake: Taking painkillers or herbal remedies without consulting a doctor.

Effect: Some medications may affect embryo implantation.

  1. Ignoring important symptoms

Mistake: Ignoring symptoms such as bleeding, severe pain, and excessive bloating.

Effect: May lead to delayed detection of complications such as ovarian hyperstimulation syndrome (OHSS).

  1. Obesity or extreme thinness

Mistake: Failure to control weight before and after the procedure.

  1. Rushing to take a pregnancy test

Mistake: Taking the test too early.

Effect: Psychological stress due to inaccurate results.

The success of IVF depends not only on the medical procedure but also on a comprehensive lifestyle. Avoiding simple mistakes can make a significant difference in the chances of pregnancy.

Dr Najeeb Layyous F.R.C.O.G

Consultant Obstetrician, Gynecologist and Infertility Specialist

The finest doctor in Jordan — may God bless him and his whole medical team. A doctor in every sense of the word. I advise anyone planning a pregnancy to visit Dr. Najeeb Layyous. His manner is wonderful, always smiling, with the highest ethics; he gives every patient her due, and the patient’s comfort matters most to him. We had been to many doctors and none understood and treated my case except him. Special thanks to him and the whole team, and to Dina in particular — a lovely person. I recommend anyone considering IVF or pregnancy to visit his clinic.
Rana · Google review

Last reviewed 17 October 2026